2. Metabolic Disease

Metabolic Disease

Metabolic Disease

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Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W745655
    1-Lauroyl-2-myristoyl-3-chloropropanediol 2828775-74-0 98%
    1-Lauroyl-2-myristoyl-3-chloropropanediol is an ester product.
    1-Lauroyl-2-myristoyl-3-chloropropanediol
  • HY-W746163
    Nervonoyl chloride 145411-43-4 98%
    Nervonoyl chloride (15(Z)-Tetracosenoyl chloride) is an ester product.
    Nervonoyl chloride
  • HY-W747206
    Traumatin 65410-38-0 98%
    Traumatin (12-Oxo-10(E)-dodecenoic acid) is an ester product.
    Traumatin
  • HY-W747255
    Cephalexin sodium 38932-40-0 98%
    Cephalexin sodium is an orally active cephalosporin Antibiotic. Cephalexin sodium disrupts bacterial cell wall synthesis and inhibits the growth of susceptible Gram-positive bacteria and some Gram-negative bacteria. Cephalexin sodium induces acute renal failure when overdosed in laboratory animals. Cephalexin sodium can be used in studies related to bacterial infections.
    Cephalexin sodium
  • HY-W747575
    (+/-)13-HODE cholesteryl ester 167354-91-8 98%
    (±)13-HODE cholesteryl ester is originally extracted from atherosclerotic lesions1 and shown to be produced by Cu2+-catalyzed oxidation of LDL. Later studies determined that 15-LO from rabbit reticulocytes and human monocytes were able to metabolize cholesteryl linoleate, a major component of LDL, to 13-HODE cholesteryl ester.
    (+/-)13-HODE cholesteryl ester
  • HY-W747703
    Hippuric acid-13C6 1163160-18-6 98%
    Hippuric acid-13C6 (Benzoylglycine-13C6) is 13C labeled Hippuric acid. Hippuric Acid is an orally active metabolite. Hippuric Acid can be produced by intestinal microorganisms from the metabolism of polyphenols, benzoic acid. Hippuric Acid decreases NRF2, MMP9 and leads to ROS accumulation. Hippuric Acid activates TGFβ/SMAD signaling. Hippuric Acid improves hyperuricemia and colitis. Hippuric Acid can also be used in cardiovascular disease research. .
    Hippuric acid-13C6
  • HY-W747992
    Indicaxanthin 2181-75-1 98%
    Indicaxanthin is a natural water-soluble betalain, presenting a yellow-orange color. Indicaxanthin possesses free radical scavenging ability and can inhibit lipid peroxidation, reducing the formation of malondialdehyde (MDA). Indicaxanthin can be used in the research of cardiovascular diseases and diabetes.
    Indicaxanthin
  • HY-W748840
    1-Stearoyl-3-oleoyl-2-chloropropanediol 1639207-45-6 98%
    1-Stearoyl-3-oleoyl-2-chloropropanediol is an ester product.
    1-Stearoyl-3-oleoyl-2-chloropropanediol
  • HY-W749404
    Clobetasone 17-Propionate 25122-56-9 98%
    Clobetasone propionate is a corticosteroid. Formulations containing clobetasol propionate have been used in the treatment of eczema, psoriasis, and lupus.
    Clobetasone 17-Propionate
  • HY-W749496
    15α-Hydroxycholestene 26758-45-2 98%
    15α-Hydroxycholestene is an oxysterol.
    15α-Hydroxycholestene
  • HY-W749497
    15β-Hydroxycholestene 26660-51-5 98%
    15β-Hydroxycholestene is an oxysterol.
    15β-Hydroxycholestene
  • HY-W749516
    Voglibose-13C3 98%
    Voglibose-13C3 is the 13C-labeled Voglibose (HY-B0025). Voglibose is an orally active alpha-glucosidase inhibitor that prevents the development of colorectal precancerous lesions induced by obesity and diabetes. Voglibose reduces oxidative stress in an inflammatory environment and inhibits the insulin-like growth factor/insulin-like growth factor-1 receptor (IGF/IGF-1R) functional axis.
    Voglibose-13C3
  • HY-W749522
    3-Oxo-4-cholestenoic acid 309762-85-4 98%
    3-Oxo-4-cholestenoic acid is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
    3-Oxo-4-cholestenoic acid
  • HY-W749532
    Cholesteryl phosphocholine 65956-64-1 98%
    Cholesteryl phosphocholine is an oxysterol.
    Cholesteryl phosphocholine
  • HY-W749569
    Vaccenic acid chloride 117485-96-8 98%
    Vaccenic acid chloride (11(E)-Octadecenoyl chloride) is an ester product.
    Vaccenic acid chloride
  • HY-W749586
    1,3-Dinonadecanoate-glycerol 372490-74-9 98%
    1,3-Dinonadecanoate-glycerol is an acylglycerol.
    1,3-Dinonadecanoate-glycerol
  • HY-W749784
    1-Decanoyl-2-lauroyl-3-chloropropanediol 2468637-80-9 98%
    1-Decanoyl-2-lauroyl-3-chloropropanediol is an ester product.
    1-Decanoyl-2-lauroyl-3-chloropropanediol
  • HY-W749873
    D-Sphingosine sulfate 56607-20-6 98%
    D-Sphingosine sulfate is an ester product.
    D-Sphingosine sulfate
  • HY-W749893
    dGDP sodium 78101-74-3 98%
    dGDP (2'-Deoxyguanosine-5'-diphosphate) sodium is a monomeric raw material that can be used for nucleic acid synthesis.
    dGDP sodium
  • HY-W749927
    (Z)-9-Heptadecenoic Acid 1981-50-6 98%
    cis-9-Heptadecenoic acid is a monounsaturated fatty acid that is a major constituent of ruminant fat and milk. The levels of cis-9-heptadecenoic acid in milk are negatively correlated with methane production in cows fed a high-lipid diet.
    (Z)-9-Heptadecenoic Acid
Cat. No. Product Name / Synonyms Application Reactivity